Mouse study: Nav1.7 Sodium Channels and OA

https://medicine.yale.edu/news-article/breakthrough-in-osteoarthritis-research-nav17-sodium-channels-unveiled-as-potential-game-changer/

Mouse study: “drugs that block Nav1.7 channels, including carbamazepine … provides substantial protection from joint damage and associated pain in the two models”

Very interesting but many mouse things don’t work in humans. Main appeal is we already use this drug – but it has many side-effects.