Feds not doing any investigation but holding on to the property anyway to block state investigations.
Cardiac cancer rare because of Nesprin-2
https://www.science.org/content/blog-post/no-heart-cancer-there-s-reason
Confess never occurred to me that hearts were weird in this way.
“silencing Nesprin-2 in tumor cells before those implantation experiments mentioned above led to robust tumor growth even in contracting cardiac muscle”
COVID becomes a cold: “patterns indicate that new strains are relatively more capable of overcoming our immune responses, but the infection outcomes are more mild”
Immunity + virus evolution + non-exposed vulnerable are dead. Annual booster uncertain value.
Open question: do all coronaviruses cause a degree of vascular brain injury? How does that accumulate over a lifespan?
Yet another constitutional crisis: Congress and war.
https://www.nytimes.com/2026/04/27/opinion/trump-iran-war-powers.html
The constitution is not what it used to be.
“my initial reaction after learning that Cook would step down as CEO of Apple was indeed along the lines of Fuck off and Good riddance”
https://morrick.me/archives/10306
I own Apple shares through index funds. Tim Cook has been great for me there. Software? Not so great. I am glad to see the back of him.
I’m not sure the mac is as dead as Mori says however. iPadOS is not doing great.
Scale of Universe: interactive zoom from the Planck to Infinity
https://scaleofuniverse.com/en
Good example of the genre
“Never Trumpers, the Always Trumpers, and then this really key group in the middle that’s pretty dispositive in terms of which way they swing and it’s dispositive in terms of determining election outcomes”
https://paulkrugman.substack.com/p/talking-vibes-with-jared-bernstein
“What I think of them, at least in the context of our conversation, are people who believed Trump when he said, “I’m going to lower prices on day one.”
It’s powerfully tempting to consider this group simply dumb. They are not academics for sure. I suspect, however, that if we disregard their explanations their distress is sending a critical message.
Lessons from the wins and losses of the Tennessee Valley Authority: “Malaria affected close to 30 percent of the population”
https://scalawagmagazine.org/2026/04/dirty-energy-and-the-lost-promise-of-the-tva/
TVA was public-private. We may be doing a lot more like that. So need to know this history.
“In the 1970s, TVA’s coal-fired facilities were responsible for about 14 percent of all toxic sulfur-dioxide emissions nationwide”
Even Palantir employees have doubts
https://www.wired.com/story/palantir-employees-are-starting-to-wonder-if-theyre-the-bad-guys/
Palantir has always been obviously evil. That employees are unhappy suggests a cultural shift.
“Expecting driverless taxis to respect bike lanes “too high a bar”
https://road.cc/news/driverless-taxis-veering-into-cycle-lanes-normal-practice-says-waymo
Bikes are the Achilles wheel of AVs
How to read Gibbon of Decline game.
https://nealstephenson.substack.com/p/bangers-from-gibbon
An extraordinary writer.
“Each dot represents a galaxy, whereas the denser areas represent regions where galaxies and galaxy clusters clump together”
Animals are kind of in the middle of the quark to universe scale
“Trump sided with Hegseth over Phelan, who was his friend and neighbor”
https://heathercoxrichardson.substack.com/p/april-23-2026
Hegseth has great power over Trump
Recognizing iPad has failed to replace the Mac.
https://mjtsai.com/blog/2026/04/15/ipados-postmacbook-neo/
Tim Cook was the iPad champion.
“App Store of 2026 is absolutely stuffed with slop, scams, and clones, propped up by an ecosystem of fake reviews”
Stolen Device Protection is a bad idea.
“I Regret the Blood Pact I Have Made With iCloud Photos”
https://mjtsai.com/blog/2026/04/24/i-regret-the-blood-pact-i-have-made-with-icloud-photos/
Apple is a terrible software partner.
Claude Code quality: “three separate issues in the Claude Code harness caused complex but material problems which directly affected users”
Anthropic screws customers with Claude Code price madness then reverses
https://simonwillison.net/2026/Apr/22/claude-code-confusion/#atom-everything
Suddenly they seem scared.
29yo MAGA bureaucrat with sex work sideline
“spent $40,000 on her over the course of three months, including first-class trips to Aruba and Italy.”
Very high end sex work.
How American health insurance games the system – prior auth
https://donmoynihan.substack.com/p/how-prior-authorizations-limit-access
If you want this fixed mandate publication of auth criteria.
A mathematician on the tedium of proving theorems.
https://davidbessis.substack.com/p/the-fall-of-the-theorem-economy
ai is good at tedium where testing is possible.
“tension between two versions of mathematics, official math and secret math.”
“the person in the White House pushing for Trump’s pointless prime time address on the Iran War was “White House chief of staff Susie Wiles,” who “thought it would reassure the country that Trump had a plan.”
https://goodpoliticsbadpolitics.substack.com/p/how-trump-does-war
She’s no James Baker.
“if you can wrap the same LLM with a thick layer of memory and experiences, it elicits behavior from the LLM that is very far from mid”
https://timkellogg.me/blog/2026/04/14/forgetting
Memory, forgetting and long lived agents. A very readable overview.
open-strix not open-claw
“need to prepare for a world where zero-day exploits are dime-a-dozen, and lots of attackers suddenly have offensive capabilities that far outstrip their skill”
Schneier praises Anthropic’s PR skills, but the crisis is truly here.
Artemis II’s Fault-Tolerant Computer
https://mjtsai.com/blog/2026/04/13/artemis-iis-fault-tolerant-computer/
A very different world.
“A minute after posting the image of himself as Jesus, Trump posted an image of a Trump tower on the moon.”
https://heathercoxrichardson.substack.com/p/april-12-2026
NEVER FORGET. Tell your grandchildren. Tell your great grandchildren.
“The land the Clovis people entered around 13,000 years ago was full of enormous ambulatory meat lockers with little-to-no experience of human predation.”
https://patrickwyman.substack.com/p/anzick-1-the-clovis-people-and-life
I loved this informed recreation of life of early Americans.
A few hundred exploded across the continent. “The sheer speed of their expansion is remarkable, and in my opinion, perhaps the clearest example of demographic success we can see anywhere in prehistory.”
Operation Enduring Glory; all the places Trump stuck his name.
https://www.contrariannews.org/p/operation-enduring-glory
America the pathetic.
THE MUSIC OF THE SPHERES BY DR. TERENCE TAO AND ZACH WEINERSMITH
“Trump told a reporter he did not know the first lady was preparing to give a speech”
https://heathercoxrichardson.substack.com/p/april-9-2026
I laughed when he called Iran “dishonorable”. That’s Classic Trump.
“hours after his wife gave an unexpected press conference about Jeffrey Epstein, Trump posted a video of a woman’s murder.”
Reminder?
A complete pizzagate nutcase is now a MN DOJ immigration “judge”
https://minnesotareformer.com/2026/04/09/right-wing-poster-is-minnesotas-newest-immigration-judge/
So many grifters, so many people with psych issues.
What is a Recession: “economists have the words to talk about what we are going through in the labor market right now because we’ve never seen it before”
https://www.kedits.com/p/what-is-a-recession
She covers a lot of territory in one informal essay. We need more economists like her.
Idaho proves the value of 1970s medicaid ACT program – by cutting the program.
“assertive community treatment”. State cut the program, then so many died that even Idaho Republicans decided to restore it.
Neutrinos still fascinate but there isn’t a sterile version.
https://www.quantamagazine.org/experiments-ring-the-death-knell-for-sterile-neutrinos-20260408/
A loose thread physicists keep picking at.
“a particle as a ripple traveling through a quantum field in space, and a massive particle as two overlapping ripples traveling through two fields”
“the American voters did resummon Nyarlathotep because enough of us remain enthralled by his unfettered madness, wanton cruelty, and nonsensical brinkmanship…”
“A study by Peking University analyzed more than a million online job postings in China between 2018 and 2024 …. functions that could be performed using AI had seen a significant decline in hiring … computer programming, accounting, editing, and sal
https://restofworld.org/2026/china-ai-anxiety-openclaw-jobs-redundancy/
The tranquility and calm of 2025 was a kind of golden age. More seriously, employment anxiety in China has multiple causes.
Academic talent is now the great class divide: “anywheres are 25–30% of the population, while somewheres are closer to 45–50%”
https://www.persuasion.community/p/david-goodhart
Most people who lack academic access or talents have an unhappy future. So they have an incentive to burn the world. Maybe that isn’t good even for the lucky 30%.
“The upshot is that for the universe to be ultrasoft, string theory is the only way”
https://www.quantamagazine.org/are-strings-still-our-best-hope-for-a-theory-of-everything-20260323/
String Theory may be a player after all.
Wyden: “secret law related to Section 702”
https://www.schneier.com/blog/archives/2026/03/sen-wyden-warns-of-another-section-702-abuse.html
NSA spies on us. No warrants.
US Senator: “a, nominee say things. In the committee that you know, the nominee knows, everybody in the room knows, are complete and utter bullshit”
https://www.contrariannews.org/p/which-cabinet-member-is-next-on-the
Yes, they aren’t stupid. They know the nominees are just bullshitting through their hearings. They ask the questions hoping it makes good TV. The awful thing is that the media plays along as though nominee hearings were actually for real. All about the clicks.
“The punch will never go away, and what we’ve done will never go away.” Sheldon compares America to an abusive husband assaulting their spouse.
“there is a fundamental conflict between the efficiency with which markets spread information and the incentives to acquire information.”
https://mattdpearce.substack.com/p/the-simple-economic-paradox-wrecking
“… Grossman-Stiglitz Paradox … Important or valuable information can be costly to obtain or produce … information gets transmitted to the rest of the marketplace when the information producers can exploit a market opening … the more widely distributed information becomes in a marketplace, you’re likelier to lose your money if you keep investing in producing high-quality information. So everyone stops producing new information”
Meds to the brain by injecting them into the skull.
https://www.science.org/content/blog-post/right-through-skull
Next drug abuse frontier. But, medically, could be awesome.
Lowe strains to describe RFK’s peptide mania: “there are indeed a whole range of physical and medical effects to be found in these things”
https://www.science.org/content/blog-post/ah-peptides-where-begin
He despairs by the end. There’s nothing to say really. It’s Darwin Awards every day now.
The regulatory burden: detailed example from a US startup.
https://rein.pk/over-regulation-is-doubling-the-cost
Regulatory ratchet is a deep problem.
New regulations are relatively easy to create and always benefit the creators in some way. It is a career ending move to remove or revise existing regulations.
Same problem Gov and industry but Gov has it worse.
HCR summarizes latest phase in the crisis: “Saudi Arabia’s Crown Prince Mohammed bin Salman (MBS), who urged Trump to start the Iran war, has invested at least $2 billion in Kushner’s private equity firm.”
https://heathercoxrichardson.substack.com/p/april-5-2026
Allegedly Trump came very close to ordering a “tactical” nuclear strike on NK in his first term.
“What migrates into silicon is not abstract reasoning but social intelligence in externalized form, encountering itself on a new substrate.”
https://www.science.org/doi/10.1126/science.aeg1895
Essay from researchers on intelligence and ai. Good description of “community of mind” emergent intelligence.
Which coup strategy will Trump try: “Some variant of terrorism is Trump’s best bet”
https://snyder.substack.com/p/the-next-coup-attempt
Trump will either leverage an actual foreign terrorist attack or create a false attack to stop midterms. Other strategies are much more challenging.
“It’s entirely possible that basically by this time Tuesday, America will have established itself as one of the world’s great villains”
https://paulkrugman.substack.com/p/living-in-hell
Anyone who aided, supported, voted for, funded, enabled the GOP … you are responsible. This is on you.
Vulnerability Research Is Cooked: “You can’t design a better problem for an LLM agent than exploitation research”
https://simonwillison.net/2026/Apr/3/vulnerability-research-is-cooked/#atom-everything
Hope you have redundant offsite archived backups.