“Colossal scientists deciphered the dire wolf genome, rewrote the genetic code of the common gray wolf to match it, and, using domestic dogs as surrogate mothers…”

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https://time.com/7274542/colossal-dire-wolf/

“Creating the dire wolves called for making just 20 edits in 14 genes in the common gray wolf … white coat, larger size, more powerful shoulders, wider head, larger teeth and jaws, more-muscular legs, and characteristic vocalizations, especially howling and whining.”

“elephant genes will simply be rewritten to match the mammoth”