“DENND1B, along with four other genes they’d linked to canine obesity, were also implicated in human obesity”

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https://gizmodo.com/when-it-comes-to-unwanted-weight-gain-humans-and-labradors-have-this-in-common-2000573900

Labradors are famous for overeating. Maybe the fat helps them survive cold water. Their metabolism is not the issue – and strict diet and exercise works.